PTEs with high CDI are more likely to be real PASs. Panel A. FDR values calculated using each of the PTEs CDI as a cutoff. The PTEs were obtained using the Ensembl database as reference and only putative PASs were considered. PTEs were ranked according to their CDI. The PTE with the highest CDI is on the first position of the scale, the PTE with the second highest CDI is on the second position, and so on until the last position with the PTE with lowest CDI. Note that the spacing between contiguous PTEs is constant independently of the absolute difference of their CDI. The FDRs obtained using as cutoffs CDIs of 1, 1.25 and 1.75 are indicated. The numbers of PTEs with a CDI equal or higher than the cutoff used are shown between brackets. Panel B. As in A using the RefSeq database as reference to obtain the PTEs.
Morgan et al. BMC Genomics 2012 13:708 doi:10.1186/1471-2164-13-708