Open Access Highly Accessed Research article

The transcriptomic fingerprint of glucoamylase over-expression in Aspergillus niger

Min Jin Kwon12, Thomas R Jørgensen13, Benjamin M Nitsche14, Mark Arentshorst1, Joohae Park1, Arthur FJ Ram12* and Vera Meyer124

Author Affiliations

1 Department Molecular Microbiology and Biotechnology, Institute of Biology Leiden, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands

2 Kluyver Centre for Genomics of Industrial Fermentation, P.O. Box 5057 2600 GA, Delft, The Netherlands

3 Novo Nordisk, Protein Expression, 2760, Måløv, Denmark

4 Institute of Biotechnology, Department Applied and Molecular Microbiology, Berlin University of Technology, Gustav-Meyer-Allee 25, 13355, Berlin, Germany

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BMC Genomics 2012, 13:701  doi:10.1186/1471-2164-13-701

Published: 13 December 2012

Additional files

Additional file 1:

Differentially expressed genes between B36 and N402 maltose-limited chemostat cultures.

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Additional file 2:

Network map based on GO-enrichment analysis using the differentially expressed, induced, and repressed gene sets in B36/N402 chemostat cultures.

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Additional file 3:

Enriched-GO terms using the differentially expressed, induced, and repressed gene sets in B36/N402 chemostat cultures.

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Additional file 4:

Four higher-order categories of enriched-GO terms using the induced gene set in B36/N402 chemostat cultures.

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Additional file 5:

Expression values of iron uptake genes.

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Additional file 6:

Expression values of protease genes.

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Additional file 7:

Enriched-GO terms from the comparison between B36/N402 versus maltose/xylose.

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Additional file 8:

Primers used in qPCR and RT PCR.

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