Pearson's correlation of miRNA-mRNA pairs vs. significant confidences of their interactions discovered by SA-BNs. A: Depiction of positive interactions from each miRNA. B: Pearson's correlation of miRNA-mRNA pairs vs. significant confidences of their interactions discovered by SA-BNs. The X-axis shows the confidence of interactions, ranging from 0 (the least confident) to 1 (the most confident), while only the statistical significant scale remains (P<0.05). The Y-axis shows the sample correlations of identified miRNA-mRNA pairs. The red and blue dots are miRNA-mRNA pairs, which are correlated at the significant level (P<0.05). It shows that the identified interactions are largely correlated, either negatively or positively, suggesting direct interactions and indirect interactions correspondingly. C: Depiction of negative interactions from each miRNA ◊miR137 □miR153 OmiR218 ×miR299-5p *miR376a XmiR122 +miR592 –miR584 -Others.
Zhou et al. BMC Genomics 2012 13:677 doi:10.1186/1471-2164-13-677