Expression analysis of putative LEF1/TCF targets in the forebrain. Volcano plots arrange genes along the dimensions of (x) mean expression fold difference between two brain structures and (y) p value (Student’s t-test). A logarithmic scale is used. Red frames surround the plot area, in which the expression in the thalamus is at least two-fold higher than in the other structures, and the difference is statistically significant (p < 0.05). The genes inside the frames are considered likely LEF1/TCF targets in the thalamus. On every plot, the genes that met the criterion of a statistically significant two-fold expression difference between the two structures are labeled. Those that are higher in the thalamus vs. cortex and hippocampus are in green. n = 6 independent biological samples.
Wisniewska et al. BMC Genomics 2012 13:635 doi:10.1186/1471-2164-13-635