Classifying stable nucleosomes containing H2A/H4R3me2s or H2A.Z using DNA sequence features. (a) Receiver Operating Characteristic (ROC) curve, demonstrating classifier performance. (b) Random forests feature importance by mean decrease in Gini index. Features have a higher frequency in H2A/H4R3me2s nucleosomal DNA (red) or H2A.Z nucleosomal DNA (blue). (c) Frequency histogram of the number of occurrences of the motif TCCATT in H2A/H4R3me2s nucleosomal DNA (red) or H2A.Z nucleosomal DNA (blue).
Capurso et al. BMC Genomics 2012 13:630 doi:10.1186/1471-2164-13-630