Example of functional prediction based on phylogenetic analysis. The protein sequences are represented by the internal identifier in PhylomeDB. Relationships among the parasite Phy000V14T_SCHMA “seed” protein (Smp_170950) and its homologs in other species (Table 1) as inferred by maximum likelihood method implemented in PhyML. Support values were computed by approximate likelihood ratio test (aLTR). Curly brackets hold Gene Ontology (GO) terms for proteins in this dataset.
Silva et al. BMC Genomics 2012 13:617 doi:10.1186/1471-2164-13-617