Heat map representation of differentially expressed genes. Based on microarray intensities, we performed hierarchical clustering of hypoxia induced genes and samples. The results indicate sharp differences between acute and chronic responses in Spalax, with clear tissue and treatment specific clades. In addition, it appears that acute hypoxia (3% and 6% O2) elicits similar responses both within and between tissues.
Malik et al. BMC Genomics 2012 13:615 doi:10.1186/1471-2164-13-615