The 251 node network is a sub-network extracted from a large mouse muscle Bayesian network of>19,500 nodes using a LG/J v SM/J differentially expressed gene set of 781 genes and their putative regulators. The nodes are colored according to differential expression; red=up regulated in LG/J vs SM/J; green = down-regulated in LG/J vs SM/J. Larger nodes are matching three out of four criteria: contained in QTL critical region; predicted key driver; significantly differentially expressed; amino acid change between strains.
Lionikas et al. BMC Genomics 2012 13:592 doi:10.1186/1471-2164-13-592