Transgenerational stability of methylation patterns in specific genes. a-h, Differential methylation levels (Log2 fold change) of promoter regions, comparing Red Junglefowl and White Leghorn, are shown with a resolution of 50-75 bp-regions in parents and offspring for each of the genes a, b, ABHD7, c, d, GAB1, e, f, KSR1, and g, h, RAPGEF1. Transcription direction and exons (blue boxes) are shown, and red arrows point at bars or groups of bars where significant levels of differential methylation are found (also indicated by red bars). Locations of CpG-islands are indicated in yellow for each region.
Nätt et al. BMC Genomics 2012 13:59 doi:10.1186/1471-2164-13-59