Table 2

List of fourteen candidate genes with related Gene Ontology (GO) categories
Sequence ID Protein homolog Ka/Ks ratio GO category GO accession
Kuku_seq_14688 Glutathione s-transferase omega 2, GSTO2 1.7284 glutathione metabolic process GO:0006749
Kuku_seq_38792 Sterol carrier protein 2, SCP2 1.4657 peroxisome organization GO:0007031
Kuku_seq_19028 Ubiquitin-specific protease 1, USP-1 1.2268 response to UV GO:0009411
Kuku_seq_38041 Ribosomal L1 domain containing 1,RSL1D1 1.1671 primary metabolic process GO:0044238
Kuku_seq_19815 Peroxiredoxin-4, PRDX4 1.1484 response to oxidative stress GO:0006979
Kuku_seq_9362 Mitochondrial translation optimization 1, MTO-1 1.1363 mitochondrial tRNA wobble uridine modification GO:0070899
Kuku_seq_22135 NADPH oxidase organizer 1, NOXO1 1.0432 NADPH oxidase complex GO:0043020
Kuku_seq_29724 Aminoacylase-1, ACY1 1.0342 protein catabolic process GO:0030163
Kuku_seq_10530 DNA repair protein xrcc, XRCC 0.6313 response to hypoxia GO:0001666
Kuku_seq_19044 4-aminobutyrate aminotransferase, ABAT 0.5899 response to hypoxia GO:0001666
Kuku_seq_19251 Cytochrome p450 4b1-like, CYP4B1 0.5867 oxygen binding GO:0019825
Kuku_seq_4377 Glutathione peroxidase 4, GPX4 0.5799 glutathione metabolic process GO:0006749
Kuku_seq_29173 V-type proton ATPase subunit G 1, V-ATPase G1 0.5173 ATP catabolic process GO:0006200
Kuku_seq_8042 Cytochrome p450 2f1-like, CYP2F1 0.5062 oxygen binding GO:0019825

These fourteen genes have Ka/Ks ratio greater than 0.5 and are most likely involved in the adaptation to high-elevation environments.

Yang et al.

Yang et al. BMC Genomics 2012 13:588   doi:10.1186/1471-2164-13-588

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