Table 1

DASE Candidate Loci Identified by both SNP- and Gene-based Approaches.*
Gene_ID SNP SNP-based Gene-based
DASE P-Value FDR DASE P-Value FDR
ACPP rs14192 3.83 0.010497 0.0442 2.32 0.005517 0.0216
ADAMTSL3 rs2277849 3.13 0.007309 0.0359 2.25 0.014546 0.0280
AGBL1 rs10520618 3.12 0.000134 0.0279 2.37 0.000305 0.0113
C1orf94 rs6698707 3.27 0.000023 0.0016 3.27 0.000024 0.0088
CEP170P1 rs28720014 3.59 0.002355 0.0180 3.59 0.002355 0.0282
CHRAC1 rs10216653 4.31 0.007459 0.0360 4.31 0.007459 0.0425
CTAGE11P rs477274 2.42 0.003269 0.0237 2.42 0.003269 0.0319
DMBT1 rs11523871 2.03 0.001676 0.0140 2.03 0.001676 0.0268
FAM154B rs16973457 2.03 0.002254 0.0423 2.03 0.002254 0.0427
FLJ39061 rs10221698 4.01 0.008501 0.0379 4.01 0.008501 0.0442
FLJ42393 rs344952 2.04 0.000490 0.0449 2.25 0.000012 0.0093
GRIN3A rs10989563 3.78 0.001589 0.0385 3.25 0.001386 0.0364
GRK4 rs1024323 2.37 0.000845 0.0532 2.71 0.000261 0.0113
rs2960306 3.01 0.000014 0.0053 - - -
HCG4 rs1611213 2.19 0.003925 0.0257 2.16 0.005494 0.0098
HLA-G rs1130363 2.52 0.001700 0.0399 3.49 0.002469 0.0170
HNRNPKP1 rs182844 2.53 0.000285 0.0071 2.53 0.000285 0.0113
HS6ST1P1 rs6423191 4.73 0.000005 0.0002 4.73 0.000005 0.0005
KHSRPP1 rs12380505 2.27 0.001212 0.0342 2.27 0.001212 0.0364
LAP3P2 rs12199346 3.55 0.000007 0.0010 3.21 0.000250 0.0113
LOC283398 rs7139313 3.74 0.000001 0.0003 2.58 0.003455 0.0178
LOC341056 rs7933723 3.70 0.002423 0.0423 3.70 0.002423 0.0428
LOC387703 rs7070947 3.61 0.000854 0.0305 3.61 0.000854 0.0355
LOC440973 rs605795 2.79 0.002160 0.0423 2.79 0.002160 0.0427
LOC442238 rs985937 4.13 0.000168 0.0114 4.13 0.000168 0.0152
LOC642590 rs9455190 3.66 0.000645 0.0486 2.50 0.000915 0.0355
LOC643618 rs732531 3.79 0.009696 0.0417 3.12 0.012274 0.0268
LOC645521 rs1976809 4.11 0.000052 0.0091 4.11 0.000052 0.0128
LOC646970 rs614805 3.38 0.008546 0.0379 3.09 0.004693 0.0207
LOC727884 rs12371762 5.21 0.002386 0.0423 4.76 0.000009 0.0002
LOC729675 rs13137565 2.36 0.003844 0.0498 2.36 0.003844 0.0522
MAGEC2 rs3765272 3.30 0.000109 0.0091 3.30 0.000109 0.0128
MMP20 rs1784423 2.32 0.001136 0.0133 2.25 0.001791 0.0268
MUC16 rs2547068 3.88 0.012106 0.0462 2.61 0.003190 0.0072
MYADML rs11684598 5.97 0.000167 0.0114 5.97 0.000167 0.0152
NLRP1 rs11651270 2.39 0.013058 0.0479 2.87 0.000835 0.0105
NSUN4 rs17361749 2.43 0.000076 0.0091 2.43 0.000076 0.0128
OR13H1 rs17316625 3.12 0.003801 0.0498 3.12 0.003801 0.0522
OR6N1 rs857825 2.78 0.002543 0.0431 2.44 0.002721 0.0443
rs857826 3.98 0.000430 0.0449 - - -
PHF2P1 rs9553323 5.08 0.000053 0.0021 4.47 0.000252 0.0048
PRDM14 rs10089937 2.07 0.002243 0.0423 2.07 0.002243 0.0427
PTCHD3 rs2484173 4.13 0.002351 0.0423 3.00 0.000427 0.0128
PTTG2 rs6811863 3.06 0.001091 0.0342 3.06 0.001091 0.0364
RPL4P4 rs13099317 4.43 0.000063 0.0011 4.43 0.000063 0.0044
RPL9P16 rs7439293 3.44 0.001159 0.0133 3.06 0.003857 0.0329
SLAMF1 rs1061217 3.42 0.000524 0.0085 3.42 0.000524 0.0137
SMARCE1P3 rs11852150 3.46 0.000020 0.0016 2.97 0.000543 0.0137
SZT2 rs2027130 2.72 0.000478 0.0085 2.39 0.003010 0.0313
TARDBPP2 rs9528094 4.81 0.000122 0.0279 2.46 0.009678 0.0454
TEX34 rs11651968 2.60 0.001264 0.0135 2.60 0.001264 0.0252
TLK2P1 rs3744516 4.00 0.004876 0.0516 4.78 0.000203 0.0046
rs4795846 5.84 0.000008 0.0053 - - -
TMCC3 rs1290005 3.45 0.002658 0.0198 2.10 0.005092 0.0209
UFM1 rs2485783 3.96 0.000659 0.0082 3.96 0.000659 0.0100
UQCRFS1P2 rs13238715 3.95 0.000097 0.0091 3.02 0.003106 0.0177
USP6 rs11658877 4.80 0.001324 0.0135 4.54 0.000530 0.0086
WASF4 rs909713 4.10 0.000063 0.0091 4.07 0.000076 0.0128
WNT3A rs752107 3.04 0.000037 0.0020 3.04 0.000037 0.0088
XIAP rs5958343 2.46 0.005591 0.0327 2.27 0.006924 0.0423
XPNPEP2 rs3747343 2.55 0.000343 0.0073 2.55 0.000343 0.0113
ZBTB8OS rs3753603 3.31 0.004053 0.0259 3.31 0.004053 0.0329
ZNF331 rs8110350 2.31 0.001826 0.0403 2.48 0.001014 0.0121

*: Only loci with DASE ≥ 2; P ≤ 0.01; and FDR ≤ 0.05 were included.

Gao et al.

Gao et al. BMC Genomics 2012 13:570   doi:10.1186/1471-2164-13-570

Open Data