Table 3 |
||||
| The top ten pathways associated with HBc-immunoprecipitated host promoter sequences with the highest enrichment scores | ||||
| Pathway | Selection counts* | p-value** | FDR*** | Enrichment score**** |
| MAPK signaling | 64 | 2.6720E-09 | 5.8516E-07 | 8.5732 |
| Wnt signaling | 41 | 2.7910E-08 | 3.0561E-06 | 7.5542 |
| Melanogenesis | 30 | 2.9928E-07 | 2.1847E-05 | 6.5239 |
| Focal adhesion (human) | 47 | 4.6332E-07 | 2.5367E-05 | 6.3341 |
| Protein processing in endoplasmic reticulum | 41 | 6.5163E-07 | 2.8541E-05 | 6.1860 |
| Long-term potentiation | 23 | 8.2838E-07 | 3.0236E-05 | 6.0818 |
| Calcium signaling | 42 | 1.2489E-06 | 3.9074E-05 | 5.9034 |
| Neurotrophin signaling | 33 | 1.7810E-06 | 4.8755E-05 | 5.7494 |
| Adherens junction | 23 | 3.1867E-06 | 7.7544E-05 | 5.4967 |
| Pathways in cancer | 64 | 3.5835E-06 | 7.8478E-05 | 5.4457 |
* Number of genes associated with the corresponding pathway.
** Enrichment p-value of the corresponding pathway as determined by Fisher’s exact test.
*** False discovery rate of the corresponding pathway.
**** Enrichment score value of the corresponding pathway, expressed as -log10(p-value).
Guo et al. BMC Genomics 2012 13:563 doi:10.1186/1471-2164-13-563
