Figure 1.

KEGG pathways analysis of predicted miR-181b target genes. KEGG pathways analysis of predicted target genes for miR-181b revealed ten significantly enriched pathways: TGF-beta signalling (p=0.0023); prostate cancer (p=0.0037); neurodegenerative diseases (p=0.0061); melanogenesis (p=0.0062); long-term potentiation (p=0.0070); T-cell receptor signalling (p=0.0087); axon guidance (p=0.0106); MAPK signalling (p=0.0217); dorso-ventral axis formation (p=0.0236); and circadian rhythms (p=0.0410). MAPK: mitogen-activated protein kinase. Predicted target genes for miR-181b were generated from the miRGen database and submitted for pathways analysis to DAVID.