Email updates

Keep up to date with the latest news and content from BMC Genomics and BioMed Central.

Open Access Highly Accessed Research article

Effects of immunostimulation on social behavior, chemical communication and genome-wide gene expression in honey bee workers (Apis mellifera)

Freddie-Jeanne Richard13*, Holly L Holt2 and Christina M Grozinger23

Author Affiliations

1 Laboratoire Ecologie Evolution Symbiose, UMR CNRS 6556, University of Poitiers, 40 avenue du Recteur Pineau, Cedex, F-86022, POITIERS, France

2 Department of Entomology, Center for Pollinator Research, Center for Chemical Ecology, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, 16802, USA

3 Previous address: Department of Entomology, North Carolina State University, Raleigh, NC, 27695, USA

For all author emails, please log on.

BMC Genomics 2012, 13:558  doi:10.1186/1471-2164-13-558

Published: 16 October 2012

Additional files

Additional file 1:

Table S1. All (670) significantly, differently expressed transcripts in Colony 1 (FDR<0.01). Table S2 All (1610) significantly, differently expressed transcripts in Colony 2 (FDR<0.01). Table S3 The 302 common, significantly, differently expressed transcripts in Colonies 1 and 2 (FDR<0.01) and their log-2 transformed, normalized, relative fold-expression values across treatment groups. Table S3b: p-values (FDR < 0.01) for all treatment pairwise comparisons (Control X Bacteria, Control X Bead, Control X Saline, Bacteria X Bead, Bacteria X Saline, Bead X Saline) for the 302 transcripts significantly regulated in both colonies (see Table S3a). Table S4 Common, significantly differentially expressed transcripts in treatment groups (control x bacteria, control x bead, control x saline) in both Colonies 1 and 2 (FDR < 0.01). Table S5 22 significantly, differentially regulated transcripts regulated by treatment (control x bacteria, control x bead, control x saline) in both Colonies 1 and 2 (FDR < 0.01). Table S6 Overrepresented GO categories (p < 0.05) amongst the 302 transcripts regulated by treatments in Colonies 1 and 2 (FDR < 0.01). Table S7 Overrepresented GO categories (p < 0.05) amongst the 22 transcripts regulated by all treatments in Colonies 1 and 2 (FDR < 0.01). Table S8 The 68 significantly, differently expressed transcripts in bacterial x control treatment groups in common between Colonies 1 and 2 (FDR<0.01). Table S9 Overrepresented GO categories (p < 0.05) amongst the 68 transcripts regulated by bacterial treatment only in Colonies 1 and 2 (FDR < 0.01). Table S10 14 genes that overlap between canonical immune genes (Evans et al., [2006]) and the 239 signficantly, differentially expressed genes in Colonies 1 and 2 (FDR < 0.01). Table S11 117 genes that were significantly regulated by Varroa infestation (Alaux et al, [2011]) and immune challenge (this study). Table S12 8 genes that were significantly regulated by immune challenge in honey bees (this study) and in Drosophila (De Gregario et al. [2011] and Roxstrom-Linquist et al. [2004]).

Format: XLSX Size: 326KB Download file

Open Data