Paired genes have a tighter transcriptional response throughout a heat shock time-course. The transcriptional response of the unpaired RRB genes (n = 213) and RP genes (n = 151) throughout a heat-shock time-course (A and B). Representative expression profiles for three representative adjacent paired RRB genes and RP genes during this stressor (C and D). The average PCC was determined by bootstrapping random pairings and the frequency is plotted for the RRB genes (E) and the RP genes (F). The actual average PCC for the unpaired genes is indicated by *, for the paired but not adjacent genes by ·, and the adjacent paired genes by #.
Arnone et al. BMC Genomics 2012 13:546 doi:10.1186/1471-2164-13-546