Table 5

Summary of supporting evidence for primary candidates examined in experiment 2
Gene QPCR P value BioLayout Profile QTL Chromosome AL vs. FR (Predicted) Literature
FSHR 0.001 Key mediator of reproductive signalling
TGFBR1 <0.001 Key mediator of cell growth + survival
SMAD3 <0.001 Promotes Cell Survival
SLIT3 0.001 Gga13 Up Promotes Apoptosis
PDGFRL <0.001 Down 5–8 mm Up Homologs involved in steroidogenesis
VDAC1 <0.001 Up in 5–8 mm Gga13 Up Central to pro-apoptotic signalling
YAP1 <0.001 Up in 5–8 mm Up Possible pro-cell survival signalling
MOSPD1 <0.001 Clustered with FSHR Up-regulated in ovarian cancer
KRT75 <0.001 Down 5–8 mm Possible Lipid Transport
SPTY2D1 <0.001 Up in 5–8 mm Down Unknown
RIGG1740 0.017 Up in 5–8 mm Down Unknown
GULP1 <0.001 Up in 5–8 mm Up Phagocytosis of apoptotic cells

McDerment et al.

McDerment et al. BMC Genomics 2012 13:494   doi:10.1186/1471-2164-13-494

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