Table 1

Effects of biological replication on power to detect DE using DESeq
% n = 2 n = 3 n = 4 n = 6 n = 8 n = 12
call rate % 0.44 1.15 1.76 3.03 4.08 5.12
FPR % 0.04 0.06 0.06 0.06 0.05 0.04
TPR % 3.26 8.95 13.95 24.30 32.72 41.57

Effects of biological replication on power to detect DE using DESeq. FPR and TPR are defined in Eqs. 5 & 6 respectively at 1%. “call rate” is the total number of reported positives / the total number of transcripts. These values are also represented in Figure 3 at 100% sequencing depth.

Robles et al.

Robles et al. BMC Genomics 2012 13:484   doi:10.1186/1471-2164-13-484

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