Table 3

Genes co-regulated with ANT2
Gene, ENSG ID Encoded protein (EnsEMBL) Protein function (UniProt)
AURKC Serine/threonine-protein kinase 13 Organizing microtubules during mitosis and chromosome segregation
105146
BTG1 B-cell translocation gene 1 protein Anti-proliferative protein, associated with the G1 phase of the cell cycle
133639
CDKN2AIP CDKN2A-interacting protein Activates p53/TP53 by CDKN2A-dependent and independent pathways
168564
CEBPB CCAAT/enhancer-binding protein beta Transcriptional activator of genes involved in immune responses
172216
CKBδ Creatine kinase B-type Transfer of phosphate between ATP and various phosphogens
166165
COL1A1 Collagen alpha-1(I) chain Type I collagen is a member of group I collagen
108821
DDIT4L* DNA damage-indu- cible transcript 4 Inhibits cell growth by regulating the TOR signaling pathway
145358
DKK1 Dickkopf-related protein 1 Antagonizes Wnt signalling by inhibiting LRP5/6 interaction with Wnt
107984
FGL1*δ Fibrinogen-like protein 1 Hepatocyte mitogenic activity
104760
GADD45B Growth arrest inducible GADD45 β Regulation of growth - apoptosis, activation of stress-responsive genes
99860
GDF15 Growth/differentiation factor 15 Transforming growth factor beta receptor signalling pathway
130513
HIF1A Hypoxia-inducible factor 1-alpha Master transcriptional regulator of the adaptive response to hypoxia
100644
KCNJ8 ATP-sensitive rectifier K+ channel 8 This potassium channel is controlled by G proteins
121361
LY96* Lymphocyte antigen 96 Cooperates with TLR4 in response to bacterial lipopolysaccharide
154589
NPPC C-type natriuretic peptide Proliferation/differentiation regulation of growth plate chondrocytes
163273
RARRES1 RAR responder protein 1 Negative regulation of cell proliferation
118849
SMCHD1 Chromosome domain maintenance ATP binding
101596

Several constructed models of the ANT2 promoter region were screened as described in Figure 1 either on the whole chromosome human sequences or the human promoter library (results with an asterisk). Function involved in cell proliferation is shown in bold characters. Genes in bold are shown overexpressed in microarrays ( Additional file 3). δNo correct probe set on Affymetrix chips corresponding to this gene. Gene IDs are with 15 numbers (ex. ENSG00000023228).

Dupont et al.

Dupont et al. BMC Genomics 2012 13:482   doi:10.1186/1471-2164-13-482

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