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Open Access Open Badges Research article

Microarray analysis revealing common and distinct functions of promyelocytic leukemia protein (PML) and tumor necrosis factor alpha (TNFα) signaling in endothelial cells

Xiwen Cheng and Hung-Ying Kao*

Author Affiliations

Department of Biochemistry, School of Medicine, Case Western Reserve University (CWRU) and the Comprehensive Cancer Center of CWRU and University Hospital of Cleveland (UHC), Cleveland, OH 44106, USA

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BMC Genomics 2012, 13:453  doi:10.1186/1471-2164-13-453

Published: 4 September 2012

Additional files

Additional file 1:

Gene lists. An excel spreadsheet containing the significantly affected gene lists and the ontology annotation information.

Format: XLSX Size: 2.4MB Download file

Open Data

Additional file 2:

Affected categories of gene ontology. An excel spreadsheet containing the significantly affected gene ontology categories.

Format: XLSX Size: 219KB Download file

Open Data

Additional file 3:

Supplemental data. A PDF file contains: supplemental materials and methods; Figure S1, the chromosomal analysis of PML target genes; Figure S2, the molecular network of PML target genes related to cell mobility and cytokine/chemokine signaling. Figure S3, the quality controls of microarray samples Figure S4, the heatmap and subclusters of the significantly affected genes by PML knockdown and TNFα treatment;

Format: PDF Size: 440KB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 4:

Raw data. An excel spreadsheet containing the background-subtracted probe level raw data.

Format: XLSX Size: 8.1MB Download file

Open Data