Table 3

Expression values of genes encoding endogenous proteases in milk somatic cells at 15, 90 and 250 days of lactation

Category

Enzyme

Gene symbol1

Day 152

Day 902

Day 2502


Cathepsins

Cathepsin B

CTSB

1062.9

4463.3

6052.5

Cathepsin D

CTSD

786.0

4007.6

4645.6

Cathepsin Z

CTSZ

222.0

1048.3

1034.0

Cathepsin H

CTSH

122.9

536.0

649.1

Cathepsin S

CTSS

89.1

507.2

642.9

Cathepsin C

CTSC

69.3

378.1

446.4

Cathepsin K

CTSK

82.1

370.5

389.8

Cathepsin A

CTSA

86.8

432.5

334.0

Cathepsin F

CTSF

22.1

76.2

103.3

Cathepsin W

CTSW

16.7

25.3

32.2

Cathepsin L2

CTSL2

10.5

12.5

13.0

Cathepsin O

CTSO

0.8

3.7

4.4

Cathepsin L1

CTSL1

0.9

0.8

0.1

Cathepsin G

CTSG

0.0

0.0

0.0


Elastase

Elastase 1

ELA1

0.4

3.2

1.2

Elastase 3B

ELA3B

0.0

0.1

0.1


Plasminogen pathway

Plasminogen

PLG

0.0

0.0

0.0

Urokinase-typeplasminogen activator

PLAU

18.7

216.8

52.2

Urokinase receptor

PLAUR

60.4

346.1

91.3

Tissue plasminogen activator

PLAT

1.9

4.2

4.8

Plasminogen activator inhibitor

SERPINE1

3.6

79.7

19.5

Plasmin inhibitor

SERPINF2

0.0

0.3

0.1


1Gene symbol according to NCBI Entrez gene database http://www.ncbi.nlm.nih.gov/gene/ webcite

2Days 15, 90 and 250 gene expressions given in RPKM

Wickramasinghe et al. BMC Genomics 2012 13:45   doi:10.1186/1471-2164-13-45

Open Data