Table 4

Unique effects of insulin neutralization on differential gene expression
Up-regulated genes Down-regulated genes
Gene symbol Gene title Fold change Gene symbol Gene title Fold change
GCG Glucagon 2.91 LOC425670 glucagon receptor precursor 2.77
TCP11L2 t-complex 11 (mouse)-like 2 2.08 BAK1 BCL2-antagonist/killer 1 1.83
LOC416916 hypothetical LOC416916 1.98 CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.62
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 1.84 SETD7 SET domain containing (lysine methyltransferase) 7 1.62
SEPT10 septin 10 1.79 ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.62
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae); similar to LSM14 homolog A (SCD6, S. cerevisiae) 1.71 AHSA1 AHA1, activator of heat shock 90 kDa protein ATPase homolog 1 (yeast) 1.62
TOE1 target of EGR1, member 1 (nuclear) 1.59
AZIN1 antizyme inhibitor 1 1.56

FDR p-value <0.05.

Ji et al.

Ji et al. BMC Genomics 2012 13:441   doi:10.1186/1471-2164-13-441

Open Data