Open Access Research article

Transcriptomic and metabolomic profiling of chicken adipose tissue in response to insulin neutralization and fasting

Bo Ji1, Ben Ernest1, Jessica R Gooding2, Suchita Das1, Arnold M Saxton1, Jean Simon3, Joelle Dupont4, Sonia Métayer-Coustard3, Shawn R Campagna2 and Brynn H Voy15*

Author Affiliations

1 Department of Animal Science, University of Tennessee, Knoxville, Tennessee, USA

2 Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA

3 Unité de Recherches Avicoles (U83), Institut National de la Recherche Agronomique (INRA), Nouzilly, 37380, France

4 Unité de Physiologie de la Reproduction et des Comportements (UMR85), Institut National de la Recherche Agronomique (INRA), Nouzilly, 37380, France

5 201E McCord Hall, Morgan Circle Dr. Knoxville, Tennessee, 2640, USA

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BMC Genomics 2012, 13:441  doi:10.1186/1471-2164-13-441

Published: 31 August 2012

Additional files

Additional file 1:

Differentially expressed genes for fasted vs. fed chickens with fold change > |1.5|. Probe ID, gene symbol, gene title and fold change are provided.

Format: XLS Size: 186KB Download file

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Additional file 2:

Differentially expressed genes for insulin neutralized vs. fed chickens. Probe ID, gene symbol, gene title and fold change are provided.

Format: XLS Size: 34KB Download file

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Additional file 3:

Metabolite levels across the three pairwise comparisons of treatments. Metabolite, fold-change and p-value are provided.

Format: XLS Size: 39KB Download file

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Additional file 4:

Metabolite-gene clusters. Cluster, metabolite,gene Ontology and KEGG annotation and benjamini corrected pvalue are provided for clusters that contained both metabolites and genes.

Format: XLS Size: 28KB Download file

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Open Data