Receiver operating curves to assess 3D colocalization of genomic elements for the human contact map. Receiver operating curves (ROC) were used to assess 3D colocalization of different genomic elements for the human contacts map of Lieberman et al. Non normalized data (left column) and normalized data (right column) were used. Only Telomeres give positive signal when using the non normalized data (curves for Centromeres, PolII are superimposed with the CTCF curve). When using the data normalized with SCN, all genomic elements tested give positive signal to the ROC test (curve for PolII is superimposed with CTCF curve).
Cournac et al. BMC Genomics 2012 13:436 doi:10.1186/1471-2164-13-436