Open Access Research article

Transcriptomics in human blood incubation reveals the importance of oxidative stress response in Saccharomyces cerevisiae clinical strains

Silvia Llopis1, Amparo Querol1, Antje Heyken2, Bernhard Hube23, Lene Jespersen4, M Teresa Fernández-Espinar1 and Roberto Pérez-Torrado1*

Author Affiliations

1 Instituto de Agroquímica y Tecnología de los Alimentos, IATA-CSIC, P.O. Box, 73. E-46100, Burjassot, Spain

2 Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology, Hans-Knoell-Institute (HKI), Jena, Germany

3 Friedrich Schiller University, Jena, Germany

4 Department of Food Science, Food Microbiology, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark

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BMC Genomics 2012, 13:419  doi:10.1186/1471-2164-13-419

Published: 23 August 2012

Additional files

Additional file 1:

Table S1. Genes and statistical significance (p-values) of the functional groups expressed at 15, 30 and 60 min of incubation in blood in virulent strains (60 and D14) and non-virulent (CECT 10.431 and W303). Table S2. Genes and statistical significance (p-values) of the functional groups repressed at 30 min of incubation in blood in virulent strains (60 and D14) and non-virulent (CECT 10431 and W303). Table S4. qRT-PCR validation of transcriptomic data. Table S5. Statistical pairwise comparisons of Figure 2. Table 6. Primers used in this study.

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Additional file 2:

Table S3. Complete microarray dataset.

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