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Open Access Research article

Optimizing the GATA-3 position weight matrix to improve the identification of novel binding sites

Soumyadeep Nandi and Ilya Ioshikhes

Author Affiliations

Ottawa Institute of Systems Biology and Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada

BMC Genomics 2012, 13:416  doi:10.1186/1471-2164-13-416

Published: 22 August 2012

Additional files

Additional file 1:

The following additional data are available with the online version of this paper (all included in one file). Additional file 1: Figure S1: z-score distribution of GATA-3 across 10 kb upstream of the EPD promoters. Additional file 1: Figure S2: Comparison of the GATA-3 z-score distribution in promoters divided with respect to the presence of Initiator element. Additional file 1: Table S1: The novel putative GATA-3 sites discovered from the EPD with location in the promoter sequences.

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