Open Access Highly Accessed Research article

The carbon starvation response of Aspergillus niger during submerged cultivation: Insights from the transcriptome and secretome

Benjamin M Nitsche12*, Thomas R Jørgensen134, Michiel Akeroyd5, Vera Meyer23 and Arthur FJ Ram13

Author Affiliations

1 Institute of Biology Leiden, Molecular Microbiology and Biotechnology, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands

2 Institute of Biotechnology, Applied and Molecular Microbiology, Berlin University of Technology, Gustav-Meyer-Allee 25, Berlin, 13355, Germany

3 Kluyver Centre for Genomics of Industrial Fermentation, Delft, PO Box 5057, 2600 GA, The Netherlands

4 Present Address: Novo Nordisk, Protein Expression, 2760 Måløv, Denmark

5 DSM Biotechnology Center, Beijerinck Laboratory, 2600 MA Delft, PO Box 1, The Netherlands

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BMC Genomics 2012, 13:380  doi:10.1186/1471-2164-13-380

Published: 8 August 2012

Additional files

Additional file 1:

Expression data. Genome-wide transcript profiles, fold changes and FDR q-values.

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Additional file 2:

GO enrichment. GO enrichment analysis of genes up-/downregulated at day 1, 3 and 6.

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Additional file 3:

Pfam enrichment. Pfam domain enrichment analysis of genes up-/downregulated at day 1, 3 and 6.

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Additional file 4:

KEGG pathway enrichment. KEGG pathway enrichment analysis of genes up-/downregulated at day 1, 3 and 6.

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Additional file 5:

Expression data fumonisin cluster. Transcript profiles, fold changes and FDR q-values for the fumonisin cluster.

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Additional file 6:

Expression data PCD genes. Transcript profiles, fold changes and FDR q-values for putative PCD associated genes.

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Additional file 7:

Secretome data. Estimated protein abundances in culture filtrates at day 1, 3 and 6.

Format: XLS Size: 237KB Download file

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