Open Access Research article

Treatment-independent miRNA signature in blood of wilms tumor patients

Jana Schmitt1*, Christina Backes1, Nasenien Nourkami-Tutdibi2, Petra Leidinger1, Stephanie Deutscher1, Markus Beier3, Manfred Gessler4, Norbert Graf2, Hans-Peter Lenhof5, Andreas Keller1 and Eckart Meese1

Author Affiliations

1 Department of Human Genetics, Saarland University, 66421 Homburg/Saar, Germany

2 Department of Pediatric Oncology and Hematology, Medical School, Saarland University, 66421 Homburg, Germany

3 febit group, 69120 Heidelberg, Germany

4 Developmental Biochemistry, Biocenter, University of Würzburg, 97074 Würzburg, Germany

5 Center for Bioinformatics, Saarland University, 66041 Saarbrücken, Germany

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BMC Genomics 2012, 13:379  doi:10.1186/1471-2164-13-379

Published: 7 August 2012

Additional files

Additional file 1:

Table S1. Patient data of Wilms tumor samples. Detailed information about the diagnosis of Wilms tumor patients. Table S2. Data of control samples. Information about age and sex of control samples.

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Additional file 2:

Table S1. Overview of significantly deregulated miRNAs in Wilms before therapy compared to normal controls. The 176 deregulated miRNAs including their fold change, p-values, and AUC values of the comparison Wims before therapy versus normal controls.

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