Open Access Research article

Discovery and validation of gene classifiers for endocrine-disrupting chemicals in zebrafish (danio rerio)

Rong-Lin Wang1*, David Bencic1, Adam Biales1, Robert Flick1, Jim Lazorchak1, Daniel Villeneuve2 and Gerald T Ankley2

Author Affiliations

1 USEPA, Ecological Exposure Research Division, National Exposure Research Laboratory, 26 W Martin Luther King Dr, Cincinnati, OH, 45268, USA

2 USEPA, Mid-Continent Ecology Division, National Health and Environmental Effects Research Laboratory, 6201 Congdon Boulevard, Duluth, MN, 55804, USA

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BMC Genomics 2012, 13:358  doi:10.1186/1471-2164-13-358

Published: 1 August 2012

Additional files

Additional file 1:

Figure S1. An illustration of GALGO algorithm as adapted from GALGO tutorial (Figure 10 and 22, version February 2006; http://biptemp.bham.ac.uk/vivo/galgo/Tutorial.pdf webcite).

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Additional file 2:

Table S1. Configurations for GA-SVM and GA-KNN search.

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Additional file 3:

Table S2. Cross mapping probe IDs between the design 015064 and 019161 by five types of evidence: Agilent BED (browser extensible data) files, Zv9 cDNA and genes from Ensemble, reference sequences (RefSeq) from GenBank, and Agilent probe sequences.

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