Table 2

miRNAs most preferentially retained within cells
miRNA Non-transfected cells & EVs miR-146a - Transfected cells & EVs
RPMM cells RPMM EV Log2(EV/Cells) RPMM cells RPMM EV Log2(EV/Cells)
mir-218 1342.24 135.00 −3.31 1460.00 132.60 −3.46
mir-15a 2411.56 435.00 −2.47 2120.00 371.28 −2.51
mir-140 1181.04 277.50 −2.09 1130.00 185.64 −2.61
mir-148b 18756.99 5047.50 −1.89 17300.00 5383.56 −1.68
mir-378 397404.00 109560.00 −1.86 192000.00 117695.76 −0.71
mir-16 7225.49 2100.00 −1.78 7190.00 2625.48 −1.45
mir-20a 45087.00 14460.00 −1.64 52700.00 14957.28 −1.82
mir-424 1230.92 397.50 −1.63 878.00 477.36 −0.88
mir-18a 4535.03 1477.50 −1.62 4520.00 1405.56 −1.69
let-7f 16253.27 5520.00 −1.56 31964.69 11055.00 −1.53
let-7 g 4999.47 1950.00 −1.36 5580.00 4826.64 −0.21
mir-130b 2194.90 877.50 −1.32 2180.00 769.08 −1.50
mir-15b 2820.93 1147.50 −1.30 2780.00 1087.32 −1.35
mir-598 1066.13 435.00 −1.29 1400.00 397.80 −1.82
mir-26b 1594.80 660.00 −1.27 1440.00 689.52 −1.06
mir-340 4503.91 2137.50 −1.08 1870.00 2280.72 0.29

Those miRNAs represented by at least 1000 reads in either cells or EV are listed. * For the transfected cells and EVs the RPMM values were calculated after removal of the reads from over-expressed miR-146a, to facilitate comparison with non-transfected samples.

Guduric-Fuchs et al.

Guduric-Fuchs et al. BMC Genomics 2012 13:357   doi:10.1186/1471-2164-13-357

Open Data