VNG0258Hgene expression in response to H2O2and oxygen. (A) Comparison of VNG0258H gene expression to that of genes involved in aerobic and anaerobic physiology . The x-axis represents shifts in oxygen levels over time in a fermentor. Graph background shading corresponds to the relative oxygen concentration. “High” oxygen represents 100% oxygen saturation in CM medium (5 μM) as measured by a dissolved oxygen probe. “Low” represents 5% saturation or below . The y-axis represents mean and variance normalized log10 expression ratios compared to mid-logarithmic phase H. salinarum. The green trace represents VNG0258H gene expression, whereas black and red traces represent the mean expression profiles for genes encoding proteins involved in aerobic and anaerobic physiology, respectively . (B) Mean gene expression profiles for clusters of genes correlated with VNG0258H mRNA changes in response to H2O2. See legend for colors. (C) Mean gene expression profiles in response to PQ for genes from (A). Colors are as in (B).
Sharma et al. BMC Genomics 2012 13:351 doi:10.1186/1471-2164-13-351