Table 2

Gene set analysis using Kyoto encyclopedia of genes and genomes (KEGG) pathways
A
Function KEGG pathway cDNA HU-6800 U133 U95
Cell cycle & DNA replication
Cell cycle 0.019 0.019 < 0.001 < 0.001
DNA replication 0.001 0.125 0.003 0.001
Base excision repair 0.003 0.003 0.002 0.003
Cell junction
Adherens junction < 0.001 < 0.001 < 0.001 0.001
Tight junction 0.004 0.003 0.002 0.006
Gap junction 0.011 0.007 0.015 0.014
Cell adhesion molecules
Focal adhesion 0.016 0.315 0.014 0.015
Cell adhesion molecules 0.007 0.007 0.017 0.005
Regulation of actin cytoskeleton 0.013 0.013 0.001 < 0.001
B cDNA HU-6800 U133 U95
Molecular pathway
Integrin signaling pathway < 0.001 0.004 0.004 0.001
VEGF signaling pathway 0.003 < 0.001 < 0.001 < 0.001
Phosphatidylinositol signaling 0.009 0.009 0.006 0.003
Wnt signaling pathway 0.004 0.524 < 0.001 < 0.001
Jak-STAT signaling pathway 0.034 0.034 < 0.001 0.003
MAPK signaling pathway 0.017 0.017 0.002 0.003
ErbB signaling pathway 0.014 0.005 0.021 0.014
p53 signaling pathway 0.035 0.034 0.016 0.006

Adjusted p-value using using Benjamini and Hochberg method as represented in four microarray platforms (significance cutoff is adjusted p-value < 0.01).

Kim et al.

Kim et al. BMC Genomics 2012 13:348   doi:10.1186/1471-2164-13-348

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