Microbial transformation from normal oral microbiota to acute endodontic infections
1 University of Maryland School of Medicine, Institute for Genome Sciences, Baltimore, MD, 20201, USA
2 University of Maryland School of Dentistry, Department of Endodontics, Prosthodontics and Operative Dentistry, Baltimore, MD, 20201, USA
3 University of Maryland School of Medicine, Department of Epidemiology and Preventive Medicine, Baltimore, MD, 20201, USA
BMC Genomics 2012, 13:345 doi:10.1186/1471-2164-13-345Published: 28 July 2012
Additional file 1:
Bar graph showing the number of reads from each sample.
Format: DOCX Size: 338KB Download file
Additional file 2:
Rarefaction curves by sample sites for each subject.
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Additional file 3:
Relative abundance (before_arcsine) and transformed abundance (after_arcsine) of all genera found in each of the samples.
Format: XLSX Size: 65KB Download file
Additional file 4:
Differentially distributed genera (p<0.05 are listed, p<0.01 are highlighted) detected using ANOVA and paired-t tests of the transformed abundance data. The original counts for each genus are listed to show that most of these organisms are not dominant organisms in the samples.
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Additional file 5:
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Additional file 6:
Differentially distributed OTUs (1% cutoff) annotated with Mothur k-mer Classifier and BLAST searches against HOMD and NCBI databases.
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Additional file 7:
Paired-t tests and ANOVA tests of systemic infection samples vs. localized infection samples.
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Additional file 8:
Table S2. Barcoded PCR primers used for the amplification of 16S rRNA genes.
Format: XLSX Size: 43KB Download file