Additional file 1.

Table S1. Commonly activated and silenced miRNAs across all sarcoma histological subtypes. A superscript 1 denotes miRNAs with potential sequence alterations. Table S2. miRNA activity patterns in osteosarcoma. Osteosarcoma-specific deregulation patterns compared to all normal tissue (p = 0.005 and FDR = 0.01). Table S3. miRNA activity patterns in osteosarcoma. Osteosarcoma-specific deregulation patterns compared to mesenchymal normal tissue (p = 0.005 and FDR = 0.01). Table S4. miRNAs commonly activated or silenced in sarcomas and epithelial cancers. Table S5. miRNAs deregulated in the “RAS active” group (p = 0.005 and FDR = 0.01). Table S6. miRNAs deregulated in the “RAS non-active” group (p = 0.005 and FDR = 0.01). Table S7. RAS-switching miRNAs by sarcoma histological subtype. Boldface denotes miRNAs which overlap with those identified in the aggregate RAS pathway analysis. Table S8. Biological themes represented in distinct miRNA activity patterns. Boldface denotes the pathways discussed in the main text of the manuscript.

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Fountzilas et al. BMC Genomics 2012 13:332   doi:10.1186/1471-2164-13-332