Open Access Research article

Sequencing and comparative genomic analysis of 1227 Felis catus cDNA sequences enriched for developmental, clinical and nutritional phenotypes

Kristopher J Irizarry12, Sukhaswami B Malladi3, Xiangming Gao3, Katherine Mitsouras24, Lynda Melendez3, Patricia A Burris3, Jeffrey A Brockman3 and Samer W Al-Murrani3*

Author Affiliations

1 College of Veterinary Medicine, Western University of Health Sciences, 309 East Second Street Pomona California, 91766, USA

2 The Applied Genomics Center, Graduate College of Biomedical Sciences, Western University of Health Sciences, Pomona California 91766, USA

3 Pet Hill's Pet Nutrition, Pet Nutrition Center, 1035 NE 43rd Street Topeka, KS 66617, USA

4 College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona California 91766, USA

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BMC Genomics 2012, 13:31  doi:10.1186/1471-2164-13-31

Published: 18 January 2012

Additional files

Additional file 1:

The cDNA and protein sequences and other information corresponding to the 1227 identified feline sequences. This table lists both the cDNA and protein sequences and corresponding lengths for each of the 1227 feline sequences we identified, along with the designation novel (314 sequences) or known (914 sequences). Sequence Identifier (unique identifier for each of the 1227 non-redundant feline sequences). Status (known denotes sequences that map to public feline sequences and novel denotes sequences with no identity to public feline sequences). cDNA Sequence Length (nucleotide length of cDNA sequence). cDNA Sequence (nucleotide sequence of cDNA). Protein Sequence Length (amino acid length of protein sequence). Protein Sequence (protein sequence corresponding to longest translation product of the cDNA).

Format: XLS Size: 2MB Download file

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Additional file 2:

Sequences and other information on orthologous sequences from the dog, human and mouse. This table contains the 914 orthologous sequences (844 known and 70 novel) and the corresponding ensembl gene, transcript and protein identifiers for the dog, human and mouse orthologs. Status (known denotes sequences that map to public feline sequences and novel denotes sequences with no identity to public feline sequences). Symbol (gene symbol). Title (gene title). Sequence Identifier (unique identifier for each non-redundant feline sequence). Cat Gene Id (cat ensembl gene identifier for sequences designated as known). Cat Transcript Id (cat ensembl transcript identifier for sequences designated as known). Cat Protein Id (cat ensembl protein identifier for subset of sequences designated as known). Dog Gene Id (ensembl gene identifier of dog ortholog). Dog Transcript Id (ensembl transcript identifier of dog ortholog). Dog Protein Id (ensembl protein identifier of dog ortholog). Human Gene Id (ensembl gene identifier of human ortholog). Human Transcript Id (ensembl transcript identifier of human ortholog). Human Protein Id (ensembl protein identifier of human ortholog). Mouse Gene Id (ensembl gene identifier of mouse ortholog). Mouse Transcript Id (ensembl transcript identifier of mouse ortholog). Mouse Protein Id (ensembl protein identifier of mouse ortholog).

Format: XLS Size: 524KB Download file

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Additional file 3:

Feline Genes Mapped to OMIM Diseases. This table contains a set of 104 feline cDNA sequences that were mapped to their corresponding human orthologs and the associated OMIM diseases. The first column indicates the cDNA identifier, the second column contains the ensembl human gene identifier for the orthologous human gene, and the third and fourth columns contain the OMIM disease identifier and the disease name respectively. Sequence Identifier (unique identifier for each non-redundant feline sequence). Human Gene Id (ensembl gene identifier of human ortholog). OMIM Identifier (OMIM id for a specific human disease). Disease Name (the name of the disease from the OMIM database).

Format: XLS Size: 48KB Download file

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