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Open Access Research article

Let-7b regulates the expression of the growth hormone receptor gene in deletion-type dwarf chickens

Shumao Lin14, Hongmei Li12, Heping Mu3, Wen Luo12, Ying Li12, Xinzheng Jia12, Sibing Wang12, Xiaolu Jia12, Qinghua Nie12, Yugu Li3* and Xiquan Zhang12*

Author Affiliations

1 Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, Guangzhou, Guangdong, 510642, China

2 Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, 510642, China

3 College of Veterinary Science, South China Agricultural University, Guangzhou, Guangdong, 510642, China

4 College of Life Science, Foshan University, Foshan, Guangdong, 528231, China

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BMC Genomics 2012, 13:306  doi:10.1186/1471-2164-13-306

Published: 10 July 2012

Additional files

Additional file 1:

Table S1. The skeletal muscle mRNA differential profile of 14-day-old embryos and 7-week-old chickens of normal chickens and dwarf chickens.

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Additional file 2:

Table S2. The summary table of prediction results of the differentially expressed.

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Additional file 3:

Table S3. The intersection genes of the differentially expressed genes of miRNA target genes and mRNA genes.

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Additional file 4:

Figure S1. The JAK-STAT signaling pathway with GHR gene involved in KEGG links the genome information with gene function. The pathway includes 111 genes in total.

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Additional file 5:

Figure S2. Adipocytokine signaling pathway with the SOCS3 gene involved in.

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Additional file 6:

Table S4. Sequences of primers used for qRT-PCR.

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Additional file 7:

Table S5. Sequences of primers used for vectors construction.

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