Open Access Research article

Transcriptome analysis reveals novel patterning and pigmentation genes underlying Heliconius butterfly wing pattern variation

Heather M Hines12*, Riccardo Papa34, Mayte Ruiz4, Alexie Papanicolaou5, Charles Wang6, H Frederik Nijhout7, W Owen McMillan18 and Robert D Reed389

  • * Corresponding author: Heather M Hines hmh19@psu.edu

  • † Equal contributors

Author Affiliations

1 Department of Genetics, North Carolina State University, Raleigh, NC, 27695, USA

2 Department of Biology, Pennsylvania State University, University Park, PA, 16802, USA

3 Department of Ecology and Evolutionary Biology, University of California, Irvine, CA, 92697, USA

4 Department of Biology and Center for Applied Tropical Ecology and Conservation, University of Puerto Rico, Rio Piedras, San Juan, Puerto Rico, 00921

5 CSIRO Ecosystem Sciences, GPO 1700, Canberra, ACT, 2601, Australia

6 Functional Genomics Core, Beckman Research Institute, City of Hope, Duarte, CA, 91010, USA

7 Department of Biology, Duke University, Durham, NC, 27708, USA

8 Smithsonian Tropical Research Institute, Panama City, Panama

9 Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY, 14853, USA

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BMC Genomics 2012, 13:288  doi:10.1186/1471-2164-13-288

Published: 29 June 2012

Additional files

Additional file 1:

Summary of the genes known to interact with optix in D. melanogaster. Genes present and differentially expressed in our study are indicated.

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Additional file 2:

Full list of all genes differentially expressed along the proximal-distal axis of the forewing. Functional clusters are based on results from gene functional classification analysis in DAVID (Table 1). Abbreviations and style follow Figure 3.

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Additional file 3:

Expression patterns and transcript IDs for genes in Table2and for additional differentially expressed pigment-related hindwing genes. Formatting of the first two columns follows Table 2. The heat map follows formatting of Figure 3, except that hindwing expression is shown (amp = H. e. amphitrite, ema = H. e. emma, fav = H. e. favorinus) and the morphs are colored respective to their color phenotype.

Format: XLS Size: 125KB Download file

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