Table 2

Summary of the most highly expressed transcripts of toxins expressed in the venom duct
Pharmacological Sites Most Frequently Targeted Rank of Site Peptides Targeting Site Sequence of Predicted Mature Venom Peptide Total Reads Distribution (% in quadrant)
P PC DC D
NMDA Receptor (NR2B Subunit) 1 ConG GEγγVQγNQγLIRγASNGKR 65,820 0.2 0.3 47.8 51.6
ConG* GEγγLQγNQγLIRγKSNGKR 90,531 0.7 0.4 34.4 64.6
Nav 1.4 (outer pore vestibule) 2 μ-GIIIA RDCCTPPKKCKDRQCKPQRCCAGR 1,090 46.0 41.6 12.5 0.0
μ-GIIIB RDCCTPPRKCKDRRCKPMKCCAGR 110,980 41.2 43.2 15.0 0.5
Nicotinic AChR (Adult Muscle, αδ interface) 3 α-GI ECCNPACGRHYSCGR 6, 431 50.7 40.4 8.6 0.4
α-GIB ECCNPACGRHYSCKGGR 29,256 24.8 60.8 13.9 0.4
α-GII ECCHPACGKHFSCGR 27,753 43.4 42.0 14.3 0.3
? Nicotinic AChR (Fetal Muscle, αγ interface) 4 αA(G4.1) CCGKPNAACHPCVCNGSCSGRR 36,087 8.8 72.9 17.5 0.8
αA(G4.2) CCGKPNAACHPCVCNGSCSGGR 4,262 4.5 79.1 15.7 0.7
αA(G4.3) CCGKPTSACHPCVCNGSCSGGR 461 20.0 62.7 16.5 0.9
Neuronal nAChR (Subtype uncertain) 5 α-GID ECCSNPACRVNNPHVCRRR 19,350 41.6 44.9 12.4 1.2
Calcium Channel (Subtype uncertain) 6 ωGVIIA ωGVIIB* CKSPGTPCSRGMRDCCTSCLLYSNKCRRY 5,992 43.9 44.6 10.1 1.3
CKSPGTPCSRTMRDCCTSCLSYSKKCRG 3,859 24.0 48.9 16.9 10.2
? Ca Channel(Unknown) 7 (G20) CVPSGGSCSRTAYSCCHGSCSGGRCG 3,767 30.2 42.3 20.7 6.7
Calcium Channel (Cav2.2 subtype, outer vestibule) 8 ωGVIA CKSPGSSCSPTSYNCCRSCNPYTKRCYG 3,611 61.0 18.6 11.3 9.2

The targets of the mature toxins, the total number of reads and their differential expression (percentage of the total) in the four segments are shown. * indicates allelic variants.

Hu et al.

Hu et al. BMC Genomics 2012 13:284   doi:10.1186/1471-2164-13-284

Open Data