Additional file 4.

Figure 2. Amino acid composition of large unannotated ORFs. The horizontal axis shows amino acids sorted by flexibility index [88].a. Amino acid composition of 1656 large unannotated non-redundant ORFs relative to proteins in the SwissProt database [89]. The amino acids Trp, Cys and Pro have twice the abundance in unannotated ORFs compared to SwissProt proteins.b. Amino acid composition of 1195 low complexity regions in unannotated ORFs relative to 1656 unannotated non-redundant ORFs. Prolines are abundant in low complexity regions, but Trp and Cys are not.

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Papenfuss et al. BMC Genomics 2012 13:261   doi:10.1186/1471-2164-13-261