Figure 2.

Comparative genome content of plasmid pMUM001. Circos [36] plot of de novo assembled contigs, for a sample of the study isolates, mapped against reference chromosome plasmid pMUM001. ISs and known genes are labelled in the outermost ring. Moving inwards, the tracks are genes coloured by functional group (lipid metabolism – black, insertion seqs – aqua, others – green). The next track marks insertion sequences in pink. The remaining tracks show selected isolates and their coverage when de novo contigs are mapped against the reference. The isolates moving inwards are: Mu_06-3845 (Benin), Mu_05142109 (Australia), Mu_L15 (USA), Mu_CC240299 (Israel), Mu_1G897 (French Guiana). The cyp150 gene (mup053) has been highlighted (grey wedge) to show its presence in African isolates and absence in other isolates.