Table 4

List of genes involved in the immune response identified between the markers flanking the peaks of the QTL detected
Chicken chr.1

QTL position

FM2position

Human chr.3 Start (pb) Gene ID4 Symbol Description Ensembl ID5
2

38.06 Mb/ 86 cM

31.78-38.35 Mb

7 32,053,542 777943 MIR148A microRNA mir-148a ENSGALG00000018281
7 32,326,549 420629 SKAP2 src kinase associated phosphoprotein 2 ENSGALG00000011051
7 32,584,271 - gga-mir-1732 microRNA-mir-1732 ENSGALG00000025254
7 32,586,148 777944 MIR196-2 microRNA mir-196-2 ENSGALG00000018282
7 32,879,740 395490 TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 ENSGALG00000011123
7 33,469,922 428436 TRIL TLR4 interactor with leucine-rich repeats -
7 33,567,743 428437 CHN2 chimerin (chimaerin) 2, involved in Rac signalling ENSGALG00000011164
3 33,985,086 420640 ANKRD28 ankyrin repeat domain 28 (promotes cell migration) ENSGALG00000011226
3 34,275,134 395109 RFTN1 raftlin, lipid raft linker 1 (B cell-specific major lipid raft protein) ENSGALG00000011241
3 34,473,226 420645 PLCL2 phospholipase C-like 2, involved in MAPK pathway and PI3K signalling ENSGALG00000011248
3 35,783,173 420649 RAB5A RAB5A, member RAS oncogene family, involve in endocytosis ENSGALG00000011272
3 37,167,138 420654 NKIRAS1 NFKB inhibitor interacting Ras-like 1 ENSGALG00000011289
19

3.38 Mb/ 21 cM

2.71- 3.80 Mb

1 2,823,176 417489 LAT2/ NTAL_CHICK Linker for activation of T cells family, member 2 ENSGALG00000001305
17 3,408,203 395930

RABEP1/

RABAPTIN1

rabaptin, RAB GTPase binding effector protein 1 ENSGALG00000001737
23

0.84 Mb/ 1 cM

0.72- 1.32

1 843,249 428208 HIVEP3 Human immunodeficiency virus type I enhancer binding protein 3 ENSGALG00000000635
26

2.95 Mb/ 29 cM

2.60-3.31 Mb

2,896,047 - gga-mir-205a microRNA-mir-205a ENSGALG00000018312
1 2,976,923 419862 TRAF3IP3 TRAF3 interacting protein 3, TNF-receptor associated interacting protein ENSGALG00000001373
1 2,989,458 419863 IRF6 Interferon regulatory factor 6 ENSGALG00000001405

1 Chicken chromosome.

2 Flanking markers.

3 Human chromosome.

4 Gene identification in NCBI database.

5 Identification of gene in Ensembl database.

Thanh-Son et al.

Thanh-Son et al. BMC Genomics 2012 13:198   doi:10.1186/1471-2164-13-198

Open Data