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Open Access Highly Accessed Research article

A neutral theory of genome evolution and the frequency distribution of genes

Bart Haegeman1 and Joshua S Weitz23

Author Affiliations

1 INRIA Research Team MODEMIC, UMR MISTEA, 34060 Montpellier, France

2 School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA

3 School of Physics, Georgia Institute of Technology, Atlanta, GA 30332, USA

BMC Genomics 2012, 13:196  doi:10.1186/1471-2164-13-196

Published: 21 May 2012

Additional files

Additional file 1:

Appendix. Composed appendix, including text and figures providing additional information on how to derive gene frequency distributions, pan and core genome scaling, and calculate model fits.

Format: PDF Size: 171KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

Gene frequency data. Raw data of the number of genes found in number of genomes for each of the 6 species analyzed here (in RTF format).

Format: RTF Size: 1KB Download file

Open Data

Additional file 3:

Model fit scripts. A set of Matlab files to estimate the best fit parameters for each of the 4 models when given gene frequency data (in RTF format).

Format: RTF Size: 11KB Download file

Open Data