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Open Access Highly Accessed Research article

RNA-seq analysis of differential gene expression in liver from lactating dairy cows divergent in negative energy balance

Matthew McCabe1, Sinéad Waters1, Dermot Morris2, David Kenny1, David Lynn1 and Chris Creevey1*

Author Affiliations

1 Animal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, Co. Meath, Ireland

2 Animal and Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Mellows Campus, Athenry, Co. Galway, Ireland

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BMC Genomics 2012, 13:193  doi:10.1186/1471-2164-13-193

Published: 20 May 2012

Additional files

Additional file 1:

Table of number and assignment of reads for each flowcell lane.

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Additional file 2:

Table SDE genes and their fold-change.

Format: XLS Size: 134KB Download file

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Additional file 3:

Comparison of microarray and RNA-seq SDE genes.

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Additional file 4:

Graph of effect of SNEB compared to MNEB on blood concentrations of major NEB associated metabolites 1–14 days post-calving.

Format: PDF Size: 334KB Download file

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Open Data

Additional file 5:

Maps of KEGG pathways (associated with ≥2 fold (FDR 0.1%) SDE genes) overrepresented in SNEB animals.

Format: PDF Size: 308KB Download file

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Open Data

Additional file 6:

Maps of KEGG pathways associated with all SDE (FDR 0.1%) genes.

Format: DOC Size: 71KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data