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Open Access Highly Accessed Research article

Estimating RNA-quality using GeneChip microarrays

Mario Fasold12 and Hans Binder12

Author Affiliations

1 Interdisciplinary Center for Bioinformatics, Universität Leipzig, Haertelstr 16-18, Leipzig, D-4107, Germany

2 LIFE - Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany

BMC Genomics 2012, 13:186  doi:10.1186/1471-2164-13-186

Published: 14 May 2012

Additional files

Additional file 1:

Supplementary text addressing the probe positional characteristics of different gene chip types; the apparent degradation index for combined specific and non-specific probe signals and the correction of the 3′/5′ bias of pobe intensities and gene expression values (L-versus-k positional scaling).

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