Additional file 8.
PI3K/Akt and mTOR genes represented in the transcriptome mapped onto a reconstruction of the pathway based on KEGG maps (KO:04150 and KO:04910). AMPKα/β/γ, 5′-AMP-activated protein kinase catalytic subunit alpha/beta/gamma; AKT2, Rac-beta serine/threonine protein kinase 2; AKT3, Rac-beta serine/threonine protein kinase 3; ATG1, Serine/threonine-protein kinase ULK1; CBL-B, E3-Ubiquitin-protein kinase CBL; CIP4 (TRIP10), Thyroid hormone receptor interactor 10; eIF4B, Eukaryotic translation initiation factor 4B; eIF4E, Eukaryotic translation initiation factor 4E; Exo-70, Exocyst complex component 7; GYS, Glycogen synthase; GSK3a, Glycogen synthase kinase 3-alpha; GLUT4, Solute carrier family 2, facilitated glucose transporter member 4; HIF1α, Hypoxia inducible factor 1-alpha; HIF3α, Hypoxia inducible factor 3-alpha; IGF, insulin-like growth factor; IGFBP, insulin-like growth factor binding protein; IRS, insulin receptor substrate; mTOR, Mammalian target of rapamycin; p110, Phosphatidylinositol 3-kinase catalytic subunit; p85, Phosphatidylinositol 3-kinase regulatory subunit; PDPK1, 3-phosphoinositide dependent protein kinase 1; PPP1R, Protein phosphatase 1 regulatory subunit; PPP1C, Protein phosphatase 1 catalytic subunit; PHKG, Phosphorylase b kinase gamma; PHK1-B, Phosphorylase kinase alpha-beta subunit; PPAR, Peroxisome proliferation-activated receptor; PYG, Starch phosphorylase; RICTOR, Rapamycin-insensitive companion of mTOR; RAPTOR, Regulatory-associated protein of mTOR; RPS70K, p70 Ribosomal protein S6 kinase; RHEB2, Ras homolog enriched brain; STRADα, STE20 related kinase adaptor alpha; S6, Ribosomal protein S6; TSC, Tuberous sclerosis; TC10 (RHOQ), Ras homolog gene family member Q; VEGF-A1, Vascular endothelial growth factor A1; v-CRK, Proto-oncogen C-crk; 4EBP1, Eukaryotic translator factor 4E binding protein. Numbers associated with the gene name represents isotig length (bp), isotig mean coverage and percentage of identity with the zebrafish orthologue.
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Garcia de la serrana et al. BMC Genomics 2012 13:181 doi:10.1186/1471-2164-13-181