Table 1

Functional classification of human genes

KOG classes

Categories

#

GC3

s.d.


INFORMATION STORAGE AND PROCESSING


[A]

RNA processing and modification

600

0.517

0.151


[B]

Chromatin structure and dynamics

224

0.610

0.172


[J]

Translation, ribosomal structure and biogenesis

1273

0.545

0.117


[K]

Transcription

1137

0.619

0.170


[L]

Replication, recombination and repair

300

0.546

0.154


CELLULAR PROCESSES AND SIGNALING


[D]

Cell cycle control, cell division, chromosome partitioning

267

0.552

0.160


[M]

Cell wall/membrane/envelope biogenesis

63

0.576

0.164


[N]

Cell motility

26

0.586

0.163


[O]

Posttranslational modification, protein turnover, chaperones

1471

0.557

0.151


[T]

Signal transduction mechanisms

2214

0.616

0.158


[U]

Intracellular trafficking, secretion, and vesicular transport

685

0.571

0.161


[V]

Defense mechanisms

1023

0.527

0.172


[W]

Extracellular structures

284

0.588

0.150


[Y]

Nuclear structure

17

0.534

0.150


[Z]

Cytoskeleton

801

0.638

0.158


METABOLISM


[C]

Energy production and conversion

403

0.576

0.153


[E]

Amino acid transport and metabolism

499

0.618

0.154


[F]

Nucleotide transport and metabolism

187

0.588

0.151


[G]

Carbohydrate transport and metabolism

469

0.606

0.150


[H]

Coenzyme transport and metabolism

102

0.563

0.135


[I]

Lipid transport and metabolism

410

0.595

0.154


[P]

Inorganic ion transport and metabolism

402

0.646

0.161


[Q]

Secondary metabolites biosynthesis, transport and catabolism

191

0.591

0.155


POORLY CHARACTERIZED


[R]

General function prediction only

1889

0.593

0.162


[S]

Function unknown

1171

0.568

0.162


Total number of genes

16118

0.584

0.160


(#) Number of genes

BernĂ¡ et al. BMC Genomics 2012 13:174   doi:10.1186/1471-2164-13-174

Open Data