Table 2

DAVID functional annotation
KEGGa term EASEb score Gene symbols
T cell receptor signaling pathway 0.002 ITK, PTPRC, PLCG1, CD8A, MAPK14, PIK3CD, SOS2, MAPK3, LCK, NFAT5, NFATC4, LCP2
Natural killer cell mediated cytotoxicity 0.003 CD48, PLCG1, PIK3CD, SOS2, MAPK3, LCK, NFAT5, NFATC4, SHC1, LCP2, NCR3
Purine metabolism 0.05 POLD3, POLE4, GDA, PDE6D, POLR3H, POLE2, ENPP1, NT5M, PDE8A, POLR2C, NME7
VEGF signaling pathway 0.004 SH2D2A, PLCG1, CASP9, MAPK14, PIK3CD, MAPK3, NFAT5, PLA2G2A, NFATC4
Fc epsilon RI signaling pathway 0.02 PLCG1, MAP2K3, MAPK14, PIK3CD, SOS2, MAPK3, PLA2G2A, LCP2
TGF-β signaling pathway 0.03 BMP4, INHBB, BMP2, RBL2, E2F5, ID2, TGFBR1, MAPK3
Pyrimidine metabolism 0.04 POLD3, POLE4, POLR3H, POLE2, NT5M, POLR2C, NME7, TK2
DNA replication 0.001 POLD3, POLE4, POLE2, PCNA, RNASEH1, RNASEH2A, MCM5
Nucleotide excision repair 0.004 POLD3, XPA, POLE4, POLE2, PCNA, CETN2, GTF2H2
Glutathione metabolism 0.03 GPX2, GSR, GPX3, GSTT2, ANPEP, MGST1
Non-small cell lung cancer 0.04 PDPK1, PLCG1, CASP9, PIK3CD, SOS2, MAPK3
Basal transcription factors 0.03 TAF2, GTF2E1, GTF2E2, TAF13, GTF2H2
Nicotinate and nicotinamide metabolism 0.05 NNT, ENPP1, NT5M, BST1

a Kyoto Encyclopedia of Genes and Genomes.

b Expression Analysis Systematic Explorer, a modified Fisher exact test.

Yehya et al.

Yehya et al. BMC Genomics 2012 13:154   doi:10.1186/1471-2164-13-154

Open Data