Figure 8.

Model for regulation of plant cell wall degrading capacity in N. crassa by WC-1/WC-2/WCC and VVD. VVD, WC-1 and WC-2 negatively affect efficiency of cellulose degradation during early stages of growth. Regulation of cellulolytic enzymes and energy supply is subject to photoadaptation by VVD, while carbon catabolite repression as mediated by CRE-1 is regulated by the WCC via VVD. Independent regulatory functions of VVD influencing cellulolytic efficiency include regulation of oxidative depolymerization, while for WC-1 and WC-2 these functions are most obvious in regulation of specific ribosomes. The WCC moreover specifically targets amino acid metabolism. Since the effect of the light response machinery is likely to be indirect, their output may involve additional target transcription factors.

Schmoll et al. BMC Genomics 2012 13:127   doi:10.1186/1471-2164-13-127
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