Analysis of selected mutant strains lacking genes with expression profiles or functions of interest for cellulase gene expression. Strains as described in Table 2 are presented according to the clusters assigned to the respective gene. Designation of strains is valid for both columns. Cultivation of strains was performed on Avicel cellulose (2% w/v) for 40 hrs. Specific cellulase activity (cellulase per biomass) and biomass content were determined and normalized to WT. Every measurement was done with at least two biological and two technical replicates. Eight biological replicates were considered for wild type. Error bars show standard deviation of the measurements considering all biological replicates.
Schmoll et al. BMC Genomics 2012 13:127 doi:10.1186/1471-2164-13-127