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Open Access Research article

Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa

Monika Schmoll12*, Chaoguang Tian13, Jianping Sun1, Doris Tisch2 and N Louise Glass1

Author Affiliations

1 Plant and Microbial Biology Department, University of California, Berkeley, CA 94720, USA

2 Research Area Gene Technology and Applied Biochemistry, Vienna University of Technology, Getreidemarkt 9, 1060 Wien, Austria

3 Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China

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BMC Genomics 2012, 13:127  doi:10.1186/1471-2164-13-127

Published: 31 March 2012

Additional files

Additional file 1:

Supplementary information. Figure S1 - Profile of total secreted proteins in wild-type and photoreceptor mutants, Figure S2 - Analysis of hyphal extension rates, Figure S3 - Experimental design for microarray analysis of photoreceptor strains, Figure S4 - Transcript abundance of major cellulase genes upon cultivation on cellulose, Figure S5 - Transcript abundance of selected cellulse and hemicellulase genes upon growth on cellulose, Table S1 - Genes with a putative function related to fenton chemistry and in oxidative depolymerization of cellulose.

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Additional file 2:

Dataset 1. Microarray data of N. crassa wild-type and photoreceptor mutants upon growth on cellulose.

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Additional file 3:

Dataset 2. Functional category analysis of genes up- or down-regulated in photoreceptor mutants.

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Additional file 4:

Dataset 3. Functional category analysis of genes assigned to coregulated clusters.

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Additional file 5:

Dataset 4. Data on specific regulation by WC-1 and/or WC-2.

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Additional file 6:

Dataset 5. Data on CPC-1 target genes regulated by WC-1 and WC-2.

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