Table 2

Summary of microRNA target sites and methylation data in gene's promoter regions

Gene categories

Mean of microRNA target sites (gene number)

Mean of mCG/CG (gene number*)

Mean of CpGO/E (gene number)

CGI number in promoter region (gene number)


Cancer genes

18.60 (379)

0.33 (381)

0.62 (381)

0.76 (412)

Dominant

19.18 (302)

0.33 (299)

0.61 (299)

0.73 (327)

Recessive

16.16 (76)

0.32 (80)

0.66 (80)

0.87 (84)

Others

14.34 (14,315)

0.53 (20,359)

0.48 (20,359)

0.53 (21,767)


CGI: CpG island. Dominant and Recessive genes are two major cancer gene categories.

*Those genes with CpG reads in their promoter region less than 3 were excluded.

Su et al. BMC Genomics 2011 12(Suppl 5):S15   doi:10.1186/1471-2164-12-S5-S15

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